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CG3735 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37803, updated on 9-Dec-2024

Summary

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Official Symbol
CG3735provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034933
Locus tag
Dmel_CG3735
See related
AllianceGenome:FB:FBgn0034933
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3735; UTP25
Summary
Predicted to enable U3 snoRNA binding activity and rRNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in embryonic/larval hypodermal muscle cell. Orthologous to human UTP25 (UTP25 small subunit processome component). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG3735 in Genome Data Viewer
Location:
60A12-60A12; 2-105 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23937077..23939754, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19824600..19827277, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44806 Neighboring gene kazachoc Neighboring gene uncharacterized protein Neighboring gene Sarco/endoplasmic reticulum Ca(2+)-ATPase Neighboring gene Transaldolase Neighboring gene G protein alpha subunit s

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. piggyBac-based insertional mutagenesis and enhancer detection as a tool for functional insect genomics. Horn C, et al. Genetics, 2003 Feb. PMID 12618403, Free PMC Article
  2. Extensive translation of small Open Reading Frames revealed by Poly-Ribo-Seq. Aspden JL, et al. Elife, 2014 Aug 21. PMID 25144939, Free PMC Article
  3. Regulation of Ribosome Biogenesis and Protein Synthesis Controls Germline Stem Cell Differentiation. Sanchez CG, et al. Cell Stem Cell, 2016 Feb 4. PMID 26669894, Free PMC Article
  4. Genetic modifiers of tauopathy in Drosophila. Shulman JM, et al. Genetics, 2003 Nov. PMID 14668378, Free PMC Article
  5. The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub. Kwong PN, et al. J Biol Chem, 2015 Dec 11. PMID 26483546, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables U3 snoRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables U3 snoRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3735-PA
CG3735-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    23937077..23939754 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299868.1 → NP_001286797.1  uncharacterized protein Dmel_CG3735, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286797.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A9UNG3, Q9W1G1
    Conserved Domains (1) summary
    pfam06862
    Location:211 → 696
    UTP25; Utp25, U3 small nucleolar RNA-associated SSU processome protein 25

  2. NM_138007.3 → NP_611851.1  uncharacterized protein Dmel_CG3735, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611851.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A9UNG3, Q9W1G1
    Related
    FBpp0072119
    Conserved Domains (1) summary
    pfam06862
    Location:211 → 696
    UTP25; Utp25, U3 small nucleolar RNA-associated SSU processome protein 25
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q960T7 Q960T7
Q9W1G1 Q9W1G1

Gene LinkOut

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