CG3803 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG3803provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0034938
Locus tag: Dmel_CG3803
See related: AllianceGenome:FB:FBgn0034938
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Dmel\CG3803
Summary: Predicted to enable oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme A biosynthetic process. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Is expressed in adult head and testis. Human ortholog(s) of this gene implicated in Leigh disease; hypertrophic cardiomyopathy; and mitochondrial complex IV deficiency nuclear type 6. Orthologous to human COX15 (cytochrome c oxidase assembly homolog COX15). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (23952513..23954048, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (19840036..19841571, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in heme A biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in heme A biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in heme A biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info

NP_611855.1

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The following sections contain reference sequences that belong to a specific genome build. Explain