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Ir60a Ionotropic receptor 60a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37881, updated on 4-Jan-2025

Summary

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Official Symbol
Ir60aprovided by FlyBase
Official Full Name
Ionotropic receptor 60aprovided by FlyBase
Primary source
FLYBASE:FBgn0034994
Locus tag
Dmel_CG13576
See related
AllianceGenome:FB:FBgn0034994
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
60a; CG13576; DmelIR60a; Dmel\CG13576; IR60a
Summary
Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in adult. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Ir60a in Genome Data Viewer
Location:
60C4-60C4; 2-106 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24249055..24251303, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20136578..20138826, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44827 Neighboring gene nord Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The multidimensional ionotropic receptors of Drosophila melanogaster. Rimal S, et al. Insect Mol Biol, 2018 Feb. PMID 28857341
  2. A Molecular and Cellular Context-Dependent Role for Ir76b in Detection of Amino Acid Taste. Ganguly A, et al. Cell Rep, 2017 Jan 17. PMID 28099851, Free PMC Article
  3. An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing. Sánchez-Alcañiz JA, et al. Nat Commun, 2018 Oct 12. PMID 30315166, Free PMC Article
  4. The Structure and Function of Ionotropic Receptors in Drosophila. Ni L. Front Mol Neurosci, 2020. PMID 33597847, Free PMC Article
  5. Molecular and cellular basis of sodium sensing in Drosophila labellum. Asefa WR, et al. iScience, 2024 Jul 19. PMID 39015148, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated monoatomic ion channel activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
ionotropic receptor 60a
Names
CG13576-PA
Ir60a-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24249055..24251303 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138057.1 → NP_611901.1  ionotropic receptor 60a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611901.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W191
    Related
    FBpp0072181, FBtr0072274
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W191 Q9W191

Gene LinkOut

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