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betaTub60D beta-Tubulin at 60D [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37888, updated on 4-Jan-2025

Summary

Official Symbol
betaTub60Dprovided by FlyBase
Official Full Name
beta-Tubulin at 60Dprovided by FlyBase
Primary source
FLYBASE:FBgn0288686
Locus tag
Dmel_CG3401
See related
AllianceGenome:FB:FBgn0288686
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
143391_i_at; 3t; B3t; BETA 60D; beta-tub; beta-Tub60D; beta-Tub6D; beta3; beta3 TU; beta3-Tub; beta3-tubulin; beta3t; beta3tub; beta3Tub; beta3TUB; beta3Tub60D; beta60C; betaTub; betaTub3; betaTub60C; betatub60D; betatubulin; beta[[3]] tubulin; beta[[3]]-Tub; beta[[3]]-tubulin; CG3401; D.m.BETA-60D; Dmbeta3; Dmel\CG3401; DTB3; p50; p50/tubulin; p53; p53/tubulin; Pin; T; Tac; Tub; Tub2E; Tub60D; tubulin
Summary
A structural constituent of cytoskeleton. Involved in axon guidance; larval behavior; and response to light stimulus. Located in microtubule. Is expressed in several structures, including gonad; imaginal disc; muscle cell; muscle system; and scolopidial dendritic cap cell. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See betaTub60D in Genome Data Viewer
Location:
60C6-60C6; 2-106 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24305881..24313099)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20193404..20200622)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene nervy Neighboring gene mir-4985 stem loop Neighboring gene Fatty acid transport protein 3 Neighboring gene long non-coding RNA:CR44810 Neighboring gene slow border cells

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in axonogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in larval behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in microtubule-based process IEA
Inferred from Electronic Annotation
more info
 
involved_in response to light stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in microtubule IDA
Inferred from Direct Assay
more info
PubMed 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
beta-Tubulin at 60D
Names
60C beta tubulin
B3-tubulin
CG3401-PA
CG3401-PB
Pin
b-3 tubulin
b3 tubulin
beta 3 tubulin
beta tubulin
beta-3 tubulin
beta-3-tubulin
beta-3tubulin
beta-Tubulin
beta-Tubulin at 60A
beta-tubulin 60D
beta-tubulin at 60D
beta-tubulin60D
beta3 tubulin
beta3-tubulin
beta3tubulin
betaTub60D-PA
betaTub60D-PB
betatubulin
tack
tubulin
tubulin b-3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24305881..24313099
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079118.3NP_523842.2  beta-Tubulin at 60D, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523842.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P08841, Q6I8M0, Q6I8M1, Q9W184
    UniProtKB/TrEMBL
    E0R982
    Related
    FBpp0072177
    Conserved Domains (2) summary
    PLN00220
    Location:1450
    PLN00220; tubulin beta chain; Provisional
    cd02187
    Location:2432
    beta_tubulin; The beta-tubulin family
  2. NM_001299906.1NP_001286835.1  beta-Tubulin at 60D, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286835.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4LGH1, E0R982
    Conserved Domains (2) summary
    PLN00220
    Location:1449
    PLN00220; tubulin beta chain; Provisional
    cd02187
    Location:2431
    beta_tubulin; The beta-tubulin family