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lhx8.L LIM homeobox 8 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379649, updated on 4-Jan-2025

Summary

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Official Symbol
lhx8.L
Official Full Name
LIM homeobox 8 L homeolog
Primary source
Xenbase:XB-GENE-866406
Locus tag
XELAEV_18022934mg
See related
EnsemblRapid:ENSXLAG00005012169 AllianceGenome:Xenbase:XB-GENE-866406
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
lhx7; lhx8; x-Lhx7
Summary
Predicted to enable DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and metal ion binding activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in musculoskeletal system; nervous system; pharyngeal arch; sensory system; and visual system. Orthologous to human LHX8 (LIM homeobox 8). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See lhx8.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (75852471..75863199, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (70555149..70565982, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene acyl-CoA dehydrogenase medium chain L homeolog Neighboring gene solute carrier family 44 member 5 L homeolog Neighboring gene uncharacterized LOC108714202 Neighboring gene tRNA-yW synthesizing protein 3 homolog L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The LIM-homeodomain gene family in the developing Xenopus brain: conservation and divergences with the mouse related to the evolution of the forebrain. Bachy I, et al. J Neurosci, 2001 Oct 1. PMID 11567052, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC68912

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
LIM homeobox 8 L homeolog; LIM/homeobox protein Lhx8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    75852471..75863199 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018256465.2 → XP_018111954.1  LIM/homeobox protein Lhx8 isoform X2

    UniProtKB/TrEMBL
    A0A1L8GLR2, A0A974D443
    Related
    ENSXLAP00005035629.1, ENSXLAT00005036522.1

  2. XM_018256466.2 → XP_018111955.1  LIM/homeobox protein Lhx8 isoform X3

    UniProtKB/TrEMBL
    A0A8J0USM9
    Related
    ENSXLAP00005035625.1, ENSXLAT00005036518.1

  3. XM_018256464.2 → XP_018111953.1  LIM/homeobox protein Lhx8 isoform X1

    UniProtKB/TrEMBL
    A0A8J0V2I3
    Related
    ENSXLAP00005035634.1, ENSXLAT00005036527.1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001086489.1: Suppressed sequence

    Description
    NM_001086489.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

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