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CG16896 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37977, updated on 4-Jan-2025

Summary

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Official Symbol
CG16896provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035073
Locus tag
Dmel_CG16896
See related
AllianceGenome:FB:FBgn0035073
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG16896
Summary
Predicted to enable GTPase activator activity. Predicted to be involved in cilium assembly. Predicted to be active in ciliary basal body. Is expressed in embryonic brain; larval ventral nerve cord; and organism. Orthologous to human TBC1D31 (TBC1 domain family member 31). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG16896 in Genome Data Viewer
Location:
60E4-60E4; 2-107 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24871407..24874912, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20758930..20762435, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44829 Neighboring gene Activating transcription factor-2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR43466

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATF-2 regulates fat metabolism in Drosophila. Okamura T, et al. Mol Biol Cell, 2007 Apr. PMID 17314398, Free PMC Article
  2. Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteins. Gabernet-Castello C, et al. Mol Biol Cell, 2013 May. PMID 23485563, Free PMC Article
  3. Evi5 promotes collective cell migration through its Rab-GAP activity. Laflamme C, et al. J Cell Biol, 2012 Jul 9. PMID 22778279, Free PMC Article
  4. A study of Epstein-Barr virus BRLF1 activity in a Drosophila model system. Adamson A, et al. ScientificWorldJournal, 2012. PMID 22629134, Free PMC Article
  5. Identification of Cellular Genes Involved in Baculovirus GP64 Trafficking to the Plasma Membrane. Hodgson JJ, et al. J Virol, 2022 Jun 22. PMID 35608346, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTPase activator activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG16896-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24871407..24874912 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138129.4 → NP_611973.2  uncharacterized protein Dmel_CG16896 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611973.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W0Z4
    Related
    FBpp0072328
    Conserved Domains (3) summary
    COG2319
    Location:228 → 467
    WD40; WD40 repeat [General function prediction only]
    cl12013
    Location:766 → 952
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    cl19107
    Location:817 → 909
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T9B7 Q8T9B7
Q9W0Z4 Q9W0Z4

Gene LinkOut

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