p130CAS - p130CAS
Involved in axonal defasciculation; cell-cell adhesion; and maintenance of cell polarity. Predicted to be located in focal adhesion. Predicted to be active in cytoplasm. Predicted to colocalize with plasma membrane. Is expressed in several structures, including amnioserosa anlage; amnioserosa primordium; dorsal ectoderm; dorsal thoracic disc; and ventral nerve cord. Human ortholog(s) of this gene implicated in breast ductal carcinoma. Orthologous to several human genes including BCAR1 (BCAR1 scaffold protein, Cas family member). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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