U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gnb3.S guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380378, updated on 27-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
gnb3.S
Official Full Name
guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog
Primary source
Xenbase:XB-GENE-6256539
Locus tag
XELAEV_18036711mg
See related
EnsemblRapid:ENSXLAG00005022556 AllianceGenome:Xenbase:XB-GENE-6256539
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
gnb3; cepg02; gnb3-a
Summary
Predicted to act upstream of or within signal transduction. Is expressed in visual system. Human ortholog(s) of this gene implicated in artery disease (multiple); congenital stationary night blindness 1H; depressive disorder; familial hyperlipidemia; and type 2 diabetes mellitus. Orthologous to human GNB3 (G protein subunit beta 3). [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See gnb3.S in Genome Data Viewer
Location:
chromosome: 7S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7S NC_054384.1 (4565572..4588666, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7S NC_030737.1 (4583493..4606472, complement)

Chromosome 7S - NC_054384.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 23 S homeolog Neighboring gene triosephosphate isomerase 1 S homeolog Neighboring gene ubiquitin specific peptidase 5 S homeolog Neighboring gene U2 spliceosomal RNA Neighboring gene prolyl 3-hydroxylase 3 S homeolog Neighboring gene tumor protein p63-regulated gene 1-like protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. An atlas of differential gene expression during early Xenopus embryogenesis. Pollet N, et al. Mech Dev, 2005 Mar. PMID 15763213
  2. Axeldb: a Xenopus laevis database focusing on gene expression. Pollet N, et al. Nucleic Acids Res, 2000 Jan 1. PMID 10592204, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC68913, MGC130764

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087217.1 → NP_001080686.1  guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog

    See identical proteins and their annotated locations for NP_001080686.1

    Status: PROVISIONAL

    Source sequence(s)
    BC056002
    UniProtKB/TrEMBL
    A0A974CB05, Q7SZU2
    Related
    ENSXLAP00005066396.1, ENSXLAT00005067920.1
    Conserved Domains (4) summary
    COG2319
    Location:49 → 340
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:48 → 340
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:58 → 95
    7WD40; WD40 repeat [structural motif]
    cl00494
    Location:1 → 36
    YbaB_DNA_bd; YbaB/EbfC DNA-binding family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    4565572..4588666 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041570382.1 → XP_041426316.1  guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1L9Z5, A0A974CB05
    Conserved Domains (2) summary
    cd00200
    Location:12 → 304
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:22 → 59
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials