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BORCS6 BLOC-1 related complex subunit 6 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38068, updated on 4-Jan-2025

Summary

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Official Symbol
BORCS6provided by FlyBase
Official Full Name
BLOC-1 related complex subunit 6provided by FlyBase
Primary source
FLYBASE:FBgn0035140
Locus tag
Dmel_CG17180
See related
AllianceGenome:FB:FBgn0035140
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17180; Dmel\CG17180
Summary
Predicted to be involved in lysosome localization. Predicted to be part of BORC complex. Orthologous to human BORCS6 (BLOC-1 related complex subunit 6). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See BORCS6 in Genome Data Viewer
Location:
61C3-61C3; 3-0.5 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (540851..542147)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (540851..542147)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene klarsicht Neighboring gene long non-coding RNA:CR45117 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46249 Neighboring gene long non-coding RNA:CR45808 Neighboring gene Cyclophilin-like Neighboring gene Homeodomain interacting protein kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila Arl8 is a general positive regulator of lysosomal fusion events. Boda A, et al. Biochim Biophys Acta Mol Cell Res, 2019 Apr. PMID 30590083
  2. A collective form of cell death requires homeodomain interacting protein kinase. Link N, et al. J Cell Biol, 2007 Aug 13. PMID 17682052, Free PMC Article
  3. Temperature, rainfall and wind variables underlie environmental adaptation in natural populations of Drosophila melanogaster. Bogaerts-Márquez M, et al. Mol Ecol, 2021 Feb. PMID 33350518, Free PMC Article
  4. Modifiers of muscle and heart cell fate specification identified by gain-of-function screen in Drosophila. Bidet Y, et al. Mech Dev, 2003 Sep. PMID 14550529
  5. Genetic modifier screens on Hairless gain-of-function phenotypes reveal genes involved in cell differentiation, cell growth and apoptosis in Drosophila melanogaster. Müller D, et al. Genetics, 2005 Nov. PMID 16118195, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in lysosome localization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of BORC complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BLOC-1 related complex subunit 6
Names
BORCS6-PA
BORCS6-PB
CG17180-PA
CG17180-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    540851..542147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138193.2 → NP_612037.1  BLOC-1 related complex subunit 6, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_612037.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T8V3, Q9W0Q3
    Related
    FBpp0072449
    Conserved Domains (1) summary
    pfam10157
    Location:142 → 301
    DUF2365; Uncharacterized conserved protein (DUF2365)

  2. NM_001274285.1 → NP_001261214.1  BLOC-1 related complex subunit 6, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261214.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T8V3, Q9W0Q3
    Conserved Domains (1) summary
    pfam10157
    Location:142 → 301
    DUF2365; Uncharacterized conserved protein (DUF2365)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T8V3 Q8T8V3
Q9W0Q3 Q9W0Q3

Gene LinkOut

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