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hng3 hinge3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38090, updated on 9-Dec-2024

Summary

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Official Symbol
hng3provided by FlyBase
Official Full Name
hinge3provided by FlyBase
Primary source
FLYBASE:FBgn0035160
Locus tag
Dmel_CG13897
See related
AllianceGenome:FB:FBgn0035160
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0118547.557; CG13897; CG13987; Dmel\CG13897
Summary
Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including embryonic/larval garland cell; embryonic/larval proventriculus; gland; imaginal disc; and larval central nervous system. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See hng3 in Genome Data Viewer
Location:
61C9-61C9; 3-0.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (737680..755489, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (737680..755489, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45411 Neighboring gene long non-coding RNA:CR43785 Neighboring gene transfer RNA:initiator Methionine-CAT 1-3 Neighboring gene extra macrochaetae Neighboring gene transfer RNA:Isoleucine-TAT 1-1 Neighboring gene transfer RNA:Isoleucine-TAT 1-2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of an arylalkylamine N-acyltransferase from Drosophila melanogaster that catalyzes the formation of long-chain N-acylserotonins. Dempsey DR, et al. FEBS Lett, 2014 Feb 14. PMID 24444601, Free PMC Article
  2. Stonewall and Brickwall: Two Partially Redundant Determinants Required for the Maintenance of Female Germline in Drosophila. Shukla V, et al. G3 (Bethesda), 2018 May 31. PMID 29669801, Free PMC Article
  3. The MADF-BESS domain factor Dip3 potentiates synergistic activation by Dorsal and Twist. Bhaskar V, et al. Gene, 2002 Oct 16. PMID 12459265
  4. Drosophila melanogaster heterochromatin protein HP1b plays important roles in transcriptional activation and development. Zhang D, et al. Chromosoma, 2011 Feb. PMID 20857302
  5. Gene duplication, lineage-specific expansion, and subfunctionalization in the MADF-BESS family patterns the Drosophila wing hinge. Shukla V, et al. Genetics, 2014 Feb. PMID 24336749, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription regulator complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
hinge3
Names
CG13897-PA
CG13897-PB
Hinge3
hng3-PA
hng3-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    737680..755489 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274293.1 → NP_001261222.1  hinge3, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261222.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PBH2, Q8SYS1
    Conserved Domains (2) summary
    smart00595
    Location:14 → 60
    MADF; subfamily of SANT domain
    pfam02944
    Location:209 → 243
    BESS; BESS motif

  2. NM_138213.3 → NP_612057.1  hinge3, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_612057.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W0N1
    Related
    FBpp0072497
    Conserved Domains (2) summary
    smart00595
    Location:5 → 91
    MADF; subfamily of SANT domain
    pfam02944
    Location:240 → 274
    BESS; BESS motif
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PBH2 M9PBH2
Q8SYS1 Q8SYS1
Q9W0N1 Q9W0N1

Gene LinkOut

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