ND-ACP NADH dehydrogenase (ubiquinone) acyl carrier protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: ND-ACPprovided by FlyBase
Official Full Name: NADH dehydrogenase (ubiquinone) acyl carrier proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0011361
Locus tag: Dmel_CG9160
See related: AllianceGenome:FB:FBgn0011361
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: ACPM; CG9160; Dmel\CG9160; dNDUFAB1; l(3)1303; l(3)j4A6; mtacp; mtACP; mtacp1; mtACP1; mtACP1A; MTACP1A; mtACP1B; MTACP1B; ND-AcC; NDUFAB1
Summary: Predicted to enable acyl binding activity and acyl carrier activity. Predicted to be involved in mitochondrial respiratory chain complex I assembly. Part of respiratory chain complex I. Is expressed in several structures, including adult head; adult heart; germline cell; gut section; and primary tracheal branch. Used to study neurodegeneration with brain iron accumulation. Orthologous to human NDUFAB1 (NADH:ubiquinone oxidoreductase subunit AB1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (1329949..1331631)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (1329949..1331631)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables acyl binding	IBA Inferred from Biological aspect of Ancestor more info
enables acyl carrier activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial electron transport, NADH to ubiquinone	IC Inferred by Curator more info	PubMed
involved_in mitochondrial respiratory chain complex I assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of mitochondrial [2Fe-2S] assembly complex	ISS Inferred from Sequence or Structural Similarity more info
is_active_in mitochondrial inner membrane	IC Inferred by Curator more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISA Inferred from Sequence Alignment more info	PubMed
part_of respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex I	IDA Inferred from Direct Assay more info	PubMed
part_of respiratory chain complex I	ISS Inferred from Sequence or Structural Similarity more info

Names: CG9160-PA; CG9160-PB; CG9160-PC; NADH ubiquinone oxidoreductase ACP; NADH ubiquinone oxidoreductase acyl carrier protein; NADH-ubiquinone oxidoreductase acyl carrier protein; NADH-ubiquinone oxidoreductase acyl-carrier subunit; NADH:ubiquinone oxidoreductase acyl carrier; ND-ACP-PA; ND-ACP-PB; ND-ACP-PC; acyl carrier protein; mitochondrial acyl carrier protein; mitochondrial acyl carrier protein 1; mitochondrial acyl carrier protein of electron transport complex I

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The following sections contain reference sequences that belong to a specific genome build. Explain