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CG7879 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38184, updated on 9-Dec-2024

Summary

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Official Symbol
CG7879provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035235
Locus tag
Dmel_CG7879
See related
AllianceGenome:FB:FBgn0035235
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg7879; Dmel\CG7879
Summary
Predicted to enable mRNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in schizophrenia 19. Orthologous to human RBM12 (RNA binding motif protein 12) and RBM12B (RNA binding motif protein 12B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG7879 in Genome Data Viewer
Location:
62A5-62A6; 3-0.5 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1559813..1568608, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1559813..1568608, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Phosphocholine cytidylyltransferase 1 Neighboring gene Phosphocholine cytidylyltransferase 2 Neighboring gene uncharacterized protein Neighboring gene Peroxin 10 Neighboring gene uncharacterized protein Neighboring gene Transmembrane endosomal protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Brain Proteome of Drosophila melanogaster Is Enriched with Nuclear Proteins. Kuznetsova KG, et al. Biochemistry (Mosc), 2019 Jan. PMID 30927528
  2. Distinct regulatory programs establish widespread sex-specific alternative splicing in Drosophila melanogaster. Hartmann B, et al. RNA, 2011 Mar. PMID 21233220, Free PMC Article
  3. Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes. Housden BE, et al. PLoS Genet, 2013. PMID 23300480, Free PMC Article
  4. Identification of alternative splicing regulators by RNA interference in Drosophila. Park JW, et al. Proc Natl Acad Sci U S A, 2004 Nov 9. PMID 15492211, Free PMC Article
  5. Selection for cold resistance alters gene transcript levels in Drosophila melanogaster. Telonis-Scott M, et al. J Insect Physiol, 2009 Jun. PMID 19232407

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of alternative mRNA splicing, via spliceosome HMP PubMed 
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IC
Inferred by Curator
more info
 PubMed 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7879-PA
CG7879-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    1559813..1568608 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_167896.2 → NP_728631.1  uncharacterized protein Dmel_CG7879, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728631.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T3I6, Q9W0D6
    Related
    FBpp0072707
    Conserved Domains (4) summary
    COG0724
    Location:364 → 551
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd00590
    Location:478 → 549
    RRM_SF; RNA recognition motif (RRM) superfamily
    cd12254
    Location:910 → 982
    RRM_hnRNPH_ESRPs_RBM12_like; RNA recognition motif found in heterogeneous nuclear ribonucleoprotein (hnRNP) H protein family, epithelial splicing regulatory proteins (ESRPs), Drosophila RNA-binding protein Fusilli, RNA-binding protein 12 (RBM12) and similar proteins
    cd12510
    Location:2 → 75
    RRM1_RBM12_like; RNA recognition motif 1 in RNA-binding protein RBM12, RBM12B and similar proteins

  2. NM_139369.2 → NP_647626.1  uncharacterized protein Dmel_CG7879, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647626.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T3I6, Q9W0D6
    Related
    FBpp0072706
    Conserved Domains (4) summary
    COG0724
    Location:364 → 551
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd00590
    Location:478 → 549
    RRM_SF; RNA recognition motif (RRM) superfamily
    cd12254
    Location:910 → 982
    RRM_hnRNPH_ESRPs_RBM12_like; RNA recognition motif found in heterogeneous nuclear ribonucleoprotein (hnRNP) H protein family, epithelial splicing regulatory proteins (ESRPs), Drosophila RNA-binding protein Fusilli, RNA-binding protein 12 (RBM12) and similar proteins
    cd12510
    Location:2 → 75
    RRM1_RBM12_like; RNA recognition motif 1 in RNA-binding protein RBM12, RBM12B and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T3I6 Q8T3I6
Q9W0D6 Q9W0D6

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