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alphaCOP - Coat Protein (coatomer) alpha

Predicted to enable structural molecule activity. Involved in male meiosis cytokinesis; protein localization to cleavage furrow; and regulation of lipid storage. Located in endoplasmic reticulum-Golgi intermediate compartment. Part of COPI vesicle coat. Is expressed in several structures, including embryonic/larval midgut primordium; epithelium; gut section; male germline cell; and mesoderm. Human ortholog(s) of this gene implicated in autoimmune interstitial lung, joint, and kidney disease. Orthologous to human COPA (COPI coat complex subunit alpha). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa