Oseg4 - Outer segment 4

Involved in cilium assembly and positive regulation of canonical Wnt signaling pathway. Located in non-motile cilium. Is expressed in several structures, including Malpighian tubule primordium; central brain primordium; epithelium; gut section; and sensory organ cell. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome; cranioectodermal dysplasia 2; and short-rib thoracic dysplasia 7 with or without polydactyly. Orthologous to human WDR35 (WD repeat domain 35). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

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