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CG2021 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38229, updated on 4-Jan-2025

Summary

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Official Symbol
CG2021provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035271
Locus tag
Dmel_CG2021
See related
AllianceGenome:FB:FBgn0035271
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG2021; l(3)62Be; l(3)neo7; neo7
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of precatalytic spliceosome. Is expressed in embryonic/larval lymph gland; embryonic/larval salivary gland; eye disc; larval central nervous system; and larval ventral nerve cord. Orthologous to human LSM8 (LSM8 homolog, U6 small nuclear RNA associated). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG2021 in Genome Data Viewer
Location:
62B4-62B4; 3-1.0 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1777010..1777411, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1777010..1777411, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Dynein heavy chain at 62B Neighboring gene antisense RNA:CR44351 Neighboring gene uncharacterized protein Neighboring gene DNA polymerase delta subunit 2 Neighboring gene alpha Spectrin Neighboring gene mitochondrial ribosomal protein L46 Neighboring gene antisense RNA:CR45834

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cell shape and interaction defects in alpha-spectrin mutants of Drosophila melanogaster. Lee JK, et al. J Cell Biol, 1993 Dec. PMID 8276898, Free PMC Article
  2. The genetics of the Dras3-Roughened-ecdysoneless chromosomal region (62B3-4 to 62D3-4) in Drosophila melanogaster: analysis of recessive lethal mutations. Sliter TJ, et al. Genetics, 1989 Oct. PMID 2511069, Free PMC Article
  3. D-Titin: a giant protein with dual roles in chromosomes and muscles. Machado C, et al. J Cell Biol, 2000 Oct 30. PMID 11062264, Free PMC Article
  4. Mapping a mutator, mu2, which increases the frequency of terminal deletions in Drosophila melanogaster. Wang M, et al. Mol Gen Genet, 1994 Dec 1. PMID 7808410
  5. The asymmetrically segregating lncRNA cherub is required for transforming stem cells into malignant cells. Landskron L, et al. Elife, 2018 Mar 27. PMID 29580384, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mRNA splicing, via spliceosome IC
Inferred by Curator
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
part_of U4/U6 x U5 tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U4/U6 x U5 tri-snRNP complex IEA
Inferred from Electronic Annotation
more info
  
part_of U6 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U6 snRNP IEA
Inferred from Electronic Annotation
more info
  
part_of U6 snRNP NAS
Non-traceable Author Statement
more info
 PubMed 
part_of precatalytic spliceosome HDA PubMed 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small nuclear ribonucleoprotein complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG2021-PA
lethal (3) 62Be

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    1777010..1777411 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139403.2 → NP_647660.1  uncharacterized protein Dmel_CG2021 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647660.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W087
    Related
    FBpp0072674
    Conserved Domains (1) summary
    cd01727
    Location:1 → 91
    LSm8; Like-Sm protein 8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W087 Q9W087

Gene LinkOut

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