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ecd ecdysoneless [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38291, updated on 9-Dec-2024

Summary

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Official Symbol
ecdprovided by FlyBase
Official Full Name
ecdysonelessprovided by FlyBase
Primary source
FLYBASE:FBgn0000543
Locus tag
Dmel_CG5714
See related
AllianceGenome:FB:FBgn0000543
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5714; Dmel\CG5714; Ecd; ecd-1; ecd1; ecdl; l(3)62Db; l(3)ecd; l(3)ecd-1; l(3)ecd1
Summary
Enables snRNP binding activity. Involved in several processes, including chitin-based embryonic cuticle biosynthetic process; embryonic morphogenesis; and mushroom body development. Located in cytoplasm. Is expressed in several structures, including egg chamber; gonad; imaginal disc; nurse cell; and ring gland. Orthologous to human ECD (ecdysoneless cell cycle regulator). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See ecd in Genome Data Viewer
Location:
62D4-62D4; 3-2 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (2263581..2265857, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (2263581..2265857, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Elongator complex protein 5 Neighboring gene peptide O-xylosyltransferase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45829 Neighboring gene obstructor-I

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Developmental analysis of Ganaspis xanthopoda, a larval parasitoid of Drosophila melanogaster. Melk JP, et al. J Exp Biol, 1999 Jul. PMID 10377270
  2. Roles of ecdysone in Drosophila development. Garen A, et al. Proc Natl Acad Sci U S A, 1977 Nov. PMID 16592466, Free PMC Article
  3. Drosophila male courtship behavior is modulated by ecdysteroids. Ganter GK, et al. J Insect Physiol, 2011 Sep. PMID 21704633, Free PMC Article
  4. Alterations in development, behavior, and physiology in Drosophila larva that have reduced ecdysone production. Li H, et al. J Neurophysiol, 2001 Jan. PMID 11152710
  5. The expression of insecticide resistance-related cytochrome P450 forms is regulated by molting hormone in Drosophila melanogaster. Spiegelman VS, et al. Biochem Biophys Res Commun, 1997 Mar 17. PMID 9125169

See all (149) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Ecd promotes U5 snRNP maturation and Prp8 stability.
    Title: Ecd promotes U5 snRNP maturation and Prp8 stability.
  2. In Drosophila cells, Ecd directly interacts with core components of the U5 snRNP spliceosomal complex.
    Title: Unexpected role of the steroid-deficiency protein ecdysoneless in pre-mRNA splicing.
  3. The transcription factor Grainy head and the steroid hormone ecdysone drive the production of two partially overlapping sets of cuticle factors.
    Title: The transcription factor Grainy head and the steroid hormone ecdysone cooperate during differentiation of the skin of Drosophila melanogaster.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables snRNP binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in Golgi organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in Malpighian tubule morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in chitin-based embryonic cuticle biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ecdysone biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
involved_in germ cell development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in germ-band shortening IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in head involution IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in instar larval development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in instar larval or pupal development TAS
Traceable Author Statement
more info
 PubMed 
involved_in lymph gland development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in molting cycle, chitin-based cuticle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mushroom body development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in oogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in progression of morphogenetic furrow involved in compound eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to symbiont IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in response to symbiont IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ecdysoneless
Names
CG5714-PA
ecd-PA
ecdysone
ecdysoneless1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    2263581..2265857 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139450.3 → NP_647707.1  ecdysoneless [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647707.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9W032
    Related
    FBpp0072781
    Conserved Domains (1) summary
    pfam07093
    Location:18 → 619
    SGT1; SGT1 protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W032.1 Q9W032

Gene LinkOut

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Chemical Information
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