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CG32486 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38367, updated on 9-Dec-2024

Summary

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Official Symbol
CG32486provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0266918
Locus tag
Dmel_CG32486
See related
AllianceGenome:FB:FBgn0266918
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0118547.267; CG14954; CG16745; Dmel\CG32486; l(2)SH3 095; l(3)SH095
Summary
Predicted to enable zinc ion binding activity. Predicted to be active in nucleus. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; epithelium; ganglia; and mesoderm. Orthologous to human ZFTRAF1 (zinc finger TRAF-type containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG32486 in Genome Data Viewer
Location:
63A5-63A6; 3-5 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3055908..3070839, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3055908..3070839, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Poly(A) specific ribonuclease subunit PAN3 Neighboring gene small nuclear RNA U5 at 63BC

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De novo piRNA cluster formation in the Drosophila germ line triggered by transgenes containing a transcribed transposon fragment. Olovnikov I, et al. Nucleic Acids Res, 2013 Jun. PMID 23620285, Free PMC Article
  2. Nutritional control of gene expression in Drosophila larvae via TOR, Myc and a novel cis-regulatory element. Li L, et al. BMC Cell Biol, 2010 Jan 20. PMID 20089194, Free PMC Article
  3. Nodal points and complexity of Notch-Ras signal integration. Hurlbut GD, et al. Proc Natl Acad Sci U S A, 2009 Feb 17. PMID 19171888, Free PMC Article
  4. The evolution of constitutively active humoral immune defenses in Drosophila populations under high parasite pressure. Zhou SO, et al. PLoS Pathog, 2024 Jan. PMID 38206983, Free PMC Article
  5. A screen for E3 ubiquitination ligases that genetically interact with the adaptor protein Cindr during Drosophila eye patterning. Ketosugbo KF, et al. PLoS One, 2017. PMID 29117266, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG32486-PD
lethal (3) SH095

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3055908..3070839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139508.3 → NP_647765.1  uncharacterized protein Dmel_CG32486 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647765.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q960J5, Q9VZV5
    Related
    FBpp0072874
    Conserved Domains (2) summary
    pfam13920
    Location:109 → 164
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
    cl19105
    Location:168 → 232
    Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VZV5.2 Q9VZV5

Gene LinkOut

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Chemical Information
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