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Slc25a34 solute carrier family 25, member 34 [ Mus musculus (house mouse) ]

Gene ID: 384071, updated on 27-Nov-2024

Summary

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Official Symbol
Slc25a34provided by MGI
Official Full Name
solute carrier family 25, member 34provided by MGI
Primary source
MGI:MGI:2686215
See related
Ensembl:ENSMUSG00000040740 AllianceGenome:MGI:2686215
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm1369
Summary
Acts upstream of or within blastocyst hatching. Located in mitochondrion. Is expressed in early conceptus. Orthologous to human SLC25A34 (solute carrier family 25 member 34). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in heart adult (RPKM 69.7), colon adult (RPKM 20.1) and 5 other tissues See more
Orthologs
human all
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Genomic context

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See Slc25a34 in Genome Data Viewer
Location:
4 D3; 4 74.64 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (141346130..141351202, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (141618819..141623891, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1289 Neighboring gene STARR-positive B cell enhancer ABC_E1662 Neighboring gene filamin binding LIM protein 1 Neighboring gene STARR-seq mESC enhancer starr_11923 Neighboring gene expressed sequence AI507597 Neighboring gene STARR-positive B cell enhancer mm9_chr4:141180986-141181286 Neighboring gene transmembrane protein 82 Neighboring gene pleckstrin homology domain containing, family M (with RUN domain) member 2 Neighboring gene predicted gene, 54266 Neighboring gene STARR-seq mESC enhancer starr_11927 Neighboring gene regulatory solute carrier protein, family 1, member 1 Neighboring gene DNA-damage inducible protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Dysregulation of Lipid and Glucose Homeostasis in Hepatocyte-Specific SLC25A34 Knockout Mice. Roy N, et al. Am J Pathol, 2022 Sep. PMID 35718058, Free PMC Article
  2. Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Cui W, et al. Sci Rep, 2016 Nov 21. PMID 27869233, Free PMC Article
  3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  4. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Clone Names

  • MGC107701

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within blastocyst hatching IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
solute carrier family 25 member 34

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013780.1 → NP_001013802.1  solute carrier family 25 member 34

    See identical proteins and their annotated locations for NP_001013802.1

    Status: PROVISIONAL

    Source sequence(s)
    AK142924, AL670446
    Consensus CDS
    CCDS18878.1
    UniProtKB/Swiss-Prot
    A2ADF7, Q5FW51
    Related
    ENSMUSP00000039188.8, ENSMUST00000038661.8
    Conserved Domains (1) summary
    pfam00153
    Location:217 → 309
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    141346130..141351202 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006538996.4 → XP_006539059.1  solute carrier family 25 member 34 isoform X1

    Conserved Domains (1) summary
    pfam00153
    Location:234 → 324
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2ADF7.1 GenPept UniProtKB/Swiss-Prot:A2ADF7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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