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Igkv4-70 immunoglobulin kappa chain variable 4-70 [ Mus musculus (house mouse) ]

Gene ID: 385120, updated on 2-Nov-2024

Summary

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Official Symbol
Igkv4-70provided by MGI
Official Full Name
immunoglobulin kappa chain variable 4-70provided by MGI
Primary source
MGI:MGI:2686348
See related
IMGT/GENE-DB:IGKV4-70; AllianceGenome:MGI:2686348
Gene type
other
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
kn4; BH151; Gm1502
Summary
Predicted to be involved in immune response. Predicted to be part of immunoglobulin complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Igkv4-70 in Genome Data Viewer
Location:
6 C1; 6 31.44 cM
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (69244872..69245396, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (69267888..69268412, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin kappa chain complex Neighboring gene immunoglobulin kappa chain variable 13-71-1 Neighboring gene STARR-seq mESC enhancer starr_16209 Neighboring gene immunoglobulin kappa chain variable 4-71 Neighboring gene immunoglobulin kappa variable 4-69 Neighboring gene immunoglobulin kappa variable 4-68

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural evidence for recognition of a single epitope by two distinct antibodies. Fleury D, et al. Proteins, 2000 Sep 1. PMID 10899782
  2. Crystallization and preliminary X-ray diffraction studies of complexes between an influenza hemagglutinin and Fab fragments of two different monoclonal antibodies. Gigant B, et al. Proteins, 1995 Sep. PMID 8539243
  3. Human myeloperoxidase in innate and acquired immunity. Arnhold J, et al. Arch Biochem Biophys, 2010 Aug 1. PMID 20399194
  4. Characteristics of the immunoglobulin Vkappa genes, pseudogenes, relics and orphons in the mouse genome. Schäble KF, et al. Eur J Immunol, 1999 Jul. PMID 10427970
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • anti-MOG Z12 variable light chain
  • anti-MOG kappa
  • immunoglobulin light chain variable region

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of immunoglobulin complex IBA
Inferred from Biological aspect of Ancestor
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_005612.1 

    Range
    1712908..1713432 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    69244872..69245396 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.