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CG4611 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38601, updated on 4-Jan-2025

Summary

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Official Symbol
CG4611provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035591
Locus tag
Dmel_CG4611
See related
AllianceGenome:FB:FBgn0035591
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4611
Summary
Predicted to enable tRNA binding activity. Predicted to be involved in tRNA 3'-end processing. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Orthologous to human PTCD1 (pentatricopeptide repeat domain 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG4611 in Genome Data Viewer
Location:
64C7-64C7; 3-13 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (5136376..5138679)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (5129476..5131779)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Yod1 deubiquitinase Neighboring gene antisense RNA:CR45160 Neighboring gene uncharacterized protein Neighboring gene Threonyl-carbamoyl synthesis 5 Neighboring gene Charged multivesicular body protein 2b Neighboring gene Dehydrogenase/reductase 4 Neighboring gene long non-coding RNA:CR45985 Neighboring gene Gdap1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The PPR domain of mitochondrial RNA polymerase is an exoribonuclease required for mtDNA replication in Drosophila melanogaster. Liu Y, et al. Nat Cell Biol, 2022 May. PMID 35449456
  2. Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila. Vesala L, et al. BMC Biol, 2024 Mar 13. PMID 38475850, Free PMC Article
  3. Identification of novel genes associated with longevity in Drosophila melanogaster - a computational approach. Hall BS, et al. Aging (Albany NY), 2019 Dec 3. PMID 31794428, Free PMC Article
  4. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article
  5. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in tRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA 3'-end processing ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial matrix ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4611-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    5136376..5138679
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139692.3 → NP_647949.1  uncharacterized protein Dmel_CG4611 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647949.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VRJ7
    Related
    FBpp0076868
    Conserved Domains (4) summary
    sd00004
    Location:186 → 213
    PPR; PPR repeat [structural motif]
    pfam01535
    Location:185 → 215
    PPR; PPR repeat
    pfam12854
    Location:252 → 284
    PPR_1; PPR repeat
    pfam13041
    Location:256 → 304
    PPR_2; PPR repeat family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VRJ7 Q9VRJ7

Gene LinkOut

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