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CG33523 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38668, updated on 9-Dec-2024

Summary

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Official Symbol
CG33523provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0053523
Locus tag
Dmel_CG33523
See related
AllianceGenome:FB:FBgn0053523
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH09028; CG10727; CG10977; CG32410; Dmel\CG33523; dVAP-B; Vap-33B
Summary
Located in endomembrane system. Is expressed in adult head and spermatozoon. Orthologous to human MOSPD2 (motile sperm domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG33523 in Genome Data Viewer
Location:
64F5-65A1; 3-16 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (5923862..5930120)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (5916962..5923220)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45167 Neighboring gene P[[i]]-sensitive XPR1 orthologue Neighboring gene uncharacterized protein Neighboring gene Regulator of chromosome condensation 1 Neighboring gene EGFR adaptor protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RDGBα localization and function at membrane contact sites is regulated by FFAT-VAP interactions. Yadav S, et al. J Cell Sci, 2018 Jan 8. PMID 29180517, Free PMC Article
  2. hVAPB, the causative gene of a heterogeneous group of motor neuron diseases in humans, is functionally interchangeable with its Drosophila homologue DVAP-33A at the neuromuscular junction. Chai A, et al. Hum Mol Genet, 2008 Jan 15. PMID 17947296, Free PMC Article
  3. Drosophila VAP-33A directs bouton formation at neuromuscular junctions in a dosage-dependent manner. Pennetta G, et al. Neuron, 2002 Jul 18. PMID 12160747
  4. Quantitative genomics of locomotor behavior in Drosophila melanogaster. Jordan KW, et al. Genome Biol, 2007. PMID 17708775, Free PMC Article
  5. Topological organisation of the phosphatidylinositol 4,5-bisphosphate-phospholipase C resynthesis cycle: PITPs bridge the ER-PM gap. Cockcroft S, et al. Biochem J, 2016 Dec 1. PMID 27888240

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum-endosome membrane contact site IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG33523-PA
CG33523-PB
CG33523-PC
CG33523-PD
CG33523-PE
CG33523-PF
MSP protein
VAMP-associated protein of 33kDa ortholog B

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    5923862..5930120
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259713.3 → NP_001246642.1  uncharacterized protein Dmel_CG33523, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246642.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NF21
    Conserved Domains (1) summary
    pfam00650
    Location:94 → 234
    CRAL_TRIO; CRAL/TRIO domain

  2. NM_001014569.4 → NP_001014569.1  uncharacterized protein Dmel_CG33523, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014569.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    I0DHK9, Q8I935
    Conserved Domains (2) summary
    pfam00635
    Location:293 → 396
    Motile_Sperm; MSP (Major sperm protein) domain
    pfam00650
    Location:94 → 234
    CRAL_TRIO; CRAL/TRIO domain

  3. NM_001274528.2 → NP_001261457.1  uncharacterized protein Dmel_CG33523, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261457.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PBR6
    Conserved Domains (2) summary
    pfam00635
    Location:293 → 396
    Motile_Sperm; MSP (Major sperm protein) domain
    pfam00650
    Location:94 → 234
    CRAL_TRIO; CRAL/TRIO domain

  4. NM_001014566.1 → NP_001014566.1  uncharacterized protein Dmel_CG33523, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014566.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3DMM9, Q9VRR4
    Conserved Domains (1) summary
    pfam00635
    Location:29 → 132
    Motile_Sperm; MSP (Major sperm protein) domain

  5. NM_001014567.2 → NP_001014567.1  uncharacterized protein Dmel_CG33523, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014567.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3DMM9, Q8I0D5
    Conserved Domains (1) summary
    pfam00635
    Location:35 → 138
    Motile_Sperm; MSP (Major sperm protein) domain

  6. NM_001014568.1 → NP_001014568.1  uncharacterized protein Dmel_CG33523, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014568.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8I934, Q8IHC4
    Conserved Domains (1) summary
    pfam00635
    Location:1 → 104
    Motile_Sperm; MSP (Major sperm protein) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9NF21 M9NF21
M9PBR6 M9PBR6
Q8I0D5 Q8I0D5
Q8I934 Q8I934
Q8I935 Q8I935
Q8IGR6 Q8IGR6
Q8IHC4 Q8IHC4
Q9VRR4 Q9VRR4

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