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Lcp65Ad Lcp65Ad [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38707, updated on 9-Dec-2024

Summary

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Official Symbol
Lcp65Adprovided by FlyBase
Official Full Name
Lcp65Adprovided by FlyBase
Primary source
FLYBASE:FBgn0020641
Locus tag
Dmel_CG6955
See related
AllianceGenome:FB:FBgn0020641
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:LP05231; CG6955; DCP1; DMCLP65d; DmelLcp65Ad; Dmel\CG6955; Lcp-d
Summary
Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be active in chitin-based extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Lcp65Ad in Genome Data Viewer
Location:
65A6-65A6; 3-16 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6143395..6144101)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6136495..6137201)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 65Av Neighboring gene Cuticular protein 65Aw Neighboring gene Lcp65Ac Neighboring gene Lcp65Ab2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Is beta-pleated sheet the molecular conformation which dictates formation of helicoidal cuticle? Iconomidou VA, et al. Insect Biochem Mol Biol, 1999 Mar. PMID 10319442
  2. A cluster of cuticle protein genes of Drosophila melanogaster at 65A: sequence, structure and evolution. Charles JP, et al. Genetics, 1997 Nov. PMID 9383064, Free PMC Article
  3. Identification of proteins and developmental expression of RNAs encoded by the 65A cuticle protein gene cluster in Drosophila melanogaster. Charles JP, et al. Insect Biochem Mol Biol, 1998 Mar. PMID 9654737
  4. TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila. Vanden Broeck L, et al. Cell Rep, 2013 Jan 31. PMID 23333275
  5. Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation. Garelli A, et al. Science, 2012 May 4. PMID 22556250

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of chitin-based larval cuticle IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of chitin-based larval cuticle ISM
Inferred from Sequence Model
more info
 PubMed 
enables structural constituent of chitin-based larval cuticle ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in chitin-based cuticle development ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in chitin-based extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in chitin-based extracellular matrix ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
Lcp65Ad
Names
CG6955-PA
CG6955-PB
Lcp65Ad-PA
Lcp65Ad-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    6143395..6144101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274537.1 → NP_001261466.1  Lcp65Ad, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261466.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    P91939, Q8IGZ8
    Conserved Domains (1) summary
    pfam00379
    Location:41 → 96
    Chitin_bind_4; Insect cuticle protein

  2. NM_057930.4 → NP_477278.1  Lcp65Ad, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477278.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    P91939, Q8IGZ8
    Related
    FBpp0076699
    Conserved Domains (1) summary
    pfam00379
    Location:41 → 96
    Chitin_bind_4; Insect cuticle protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P91939 P91939
Q8IGZ8 Q8IGZ8

Gene LinkOut

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