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Ssxb2 SSX member B2 [ Mus musculus (house mouse) ]

Gene ID: 387132, updated on 27-Nov-2024

Summary

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Official Symbol
Ssxb2provided by MGI
Official Full Name
SSX member B2provided by MGI
Primary source
MGI:MGI:2446771
See related
Ensembl:ENSMUSG00000023165 AllianceGenome:MGI:2446771
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be active in nucleus. Orthologous to human SSX4 (SSX family member 4) and SSX4B (SSX family member 4B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Ssxb2 in Genome Data Viewer
Location:
X A1.1; X 3.83 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (8320582..8327965, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (8454343..8461726, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene SSX member B9 Neighboring gene STARR-seq mESC enhancer starr_46696 Neighboring gene SSX member B1 Neighboring gene SSX member B15 Neighboring gene SSX member B6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification and characterization of mouse SSX genes: a multigene family on the X chromosome with restricted cancer/testis expression. Chen YT, et al. Genomics, 2003 Dec. PMID 14611804
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
synovial sarcoma, X member B, breakpoint 2
Names
synovial sarcoma, X member B2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001450.4 → NP_001001450.1  synovial sarcoma, X member B, breakpoint 2 isoform 1

    See identical proteins and their annotated locations for NP_001001450.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AY244793, BC048441
    Consensus CDS
    CCDS29998.1
    UniProtKB/TrEMBL
    Q8C5Z3
    Conserved Domains (3) summary
    cd07765
    Location:61 → 98
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:60 → 115
    KRAB; krueppel associated box
    pfam09514
    Location:130 → 149
    SSXRD; SSXRD motif

  2. NM_001134226.1 → NP_001127698.1  synovial sarcoma, X member B, breakpoint 2 isoform 2

    See identical proteins and their annotated locations for NP_001127698.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and lacks a portion of the 5' coding region, compared to variant 1. This results in translation initiation at a downstream start codon and an isoform (2) with a shorter N-terminal than isoform 1.
    Source sequence(s)
    BC048441
    Consensus CDS
    CCDS52991.1
    UniProtKB/TrEMBL
    Q80ZT4
    Related
    ENSMUSP00000100065.3, ENSMUST00000103000.9
    Conserved Domains (2) summary
    cd07765
    Location:24 → 61
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:23 → 78
    KRAB; krueppel associated box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    8320582..8327965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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