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CG10147 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38733, updated on 4-Jan-2025

Summary

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Official Symbol
CG10147provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035702
Locus tag
Dmel_CG10147
See related
AllianceGenome:FB:FBgn0035702
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10147
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in embryonic brain; larval ventral nerve cord; and organism. Orthologous to human ZBTB48 (zinc finger and BTB domain containing 48). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG10147 in Genome Data Viewer
Location:
65B3-65B3; 3-17 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6486167..6488424, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6479267..6481524, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45980 Neighboring gene uncharacterized protein Neighboring gene bulli Neighboring gene Vacuolar protein sorting 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sox21b underlies the rapid diversification of a novel male genital structure between Drosophila species. Ridgway AM, et al. Curr Biol, 2024 Mar 11. PMID 38309269
  2. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article
  3. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. Kasinathan B, et al. Elife, 2020 Nov 10. PMID 33169670, Free PMC Article
  4. Genomics of Recombination Rate Variation in Temperature-Evolved Drosophila melanogaster Populations. Winbush A, et al. Genome Biol Evol, 2021 Jan 7. PMID 33247719, Free PMC Article
  5. Rapid and efficient cDNA library screening by self-ligation of inverse PCR products (SLIP). Hoskins RA, et al. Nucleic Acids Res, 2005 Dec 2. PMID 16326860, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription cis-regulatory region binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10147-PA
CG10147-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    6486167..6488424 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274548.1 → NP_001261477.1  uncharacterized protein Dmel_CG10147, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261477.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VRX0
    Conserved Domains (3) summary
    smart00868
    Location:7 → 80
    zf-AD; Zinc-finger associated domain (zf-AD)
    sd00017
    Location:352 → 373
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam15909
    Location:199 → 287
    zf-C2H2_8; C2H2-type zinc ribbon

  2. NM_139789.2 → NP_648046.1  uncharacterized protein Dmel_CG10147, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648046.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VRX0
    Related
    FBpp0076696
    Conserved Domains (3) summary
    smart00868
    Location:7 → 80
    zf-AD; Zinc-finger associated domain (zf-AD)
    sd00017
    Location:352 → 373
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam15909
    Location:199 → 287
    zf-C2H2_8; C2H2-type zinc ribbon
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VRX0 Q9VRX0

Gene LinkOut

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