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vvl ventral veins lacking [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38752, updated on 9-Dec-2024

Summary

Official Symbol
vvlprovided by FlyBase
Official Full Name
ventral veins lackingprovided by FlyBase
Primary source
FLYBASE:FBgn0086680
Locus tag
Dmel_CG10037
See related
AllianceGenome:FB:FBgn0086680
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Cf1-a; Cf1a; CF1A; Cf1a/drifter; Cf1a/drifter/vvl; Cfla; CG10037; dfr; Dfr; DFR; dfr-vvl; dfr/vvl; Dfr/Vvl; Dmel\CG10037; drf; Drf; prd3; sep; ut; Vv1; Vvl; VVL; vvl/dfr; vvl/dfr/ut
Summary
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in nervous system development; positive regulation of macromolecule biosynthetic process; and regulation of dendrite morphogenesis. Located in nucleus. Is expressed in several structures, including adult optic lobe neurons; adult uniglomerular antennal lobe projection neuron lPN; epithelium; ganglia; and gut section. Human ortholog(s) of this gene implicated in X-linked deafness 2. Orthologous to several human genes including POU3F4 (POU class 3 homeobox 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See vvl in Genome Data Viewer
Location:
65C5-65C5; 3-17 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6790158..6794941)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6783258..6788041)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Radial spoke head protein 3 Neighboring gene long non-coding RNA:CR45759 Neighboring gene long non-coding RNA:CR45115 Neighboring gene long non-coding RNA:CR45416

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ventral veins lacking
Names
CG10037-PA
CG10037-PC
CG10037-PD
CG10037-PE
CG10037-PF
Drifter/Ventral veinless
PRD gene 3
U-turned
drifter
paired-like 3
separated
u-turn
ventral veinless
vvl-PA
vvl-PC
vvl-PD
vvl-PE
vvl-PF

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    6790158..6794941
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300028.1NP_001286957.1  ventral veins lacking, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286957.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P16241, Q24460, Q86P26, Q9VRY9
    UniProtKB/TrEMBL
    A8E6G8
    Conserved Domains (2) summary
    smart00352
    Location:212286
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:307361
    Homeobox; Homeobox domain
  2. NM_079224.5NP_523948.1  ventral veins lacking, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523948.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P16241, Q24460, Q86P26, Q9VRY9
    UniProtKB/TrEMBL
    A8E6G8
    Related
    FBpp0076653
    Conserved Domains (2) summary
    smart00352
    Location:212286
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:307361
    Homeobox; Homeobox domain
  3. NM_001169884.2NP_001163355.2  ventral veins lacking, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163355.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JI48
    Conserved Domains (2) summary
    smart00352
    Location:212286
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:307360
    Homeobox; Homeobox domain
  4. NM_001316454.1NP_001303383.1  ventral veins lacking, isoform E [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0S0WNN1
    Conserved Domains (2) summary
    smart00352
    Location:212286
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:307360
    Homeobox; Homeobox domain
  5. NM_001316455.1NP_001303384.1  ventral veins lacking, isoform F [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0S0WGV5
    Conserved Domains (2) summary
    smart00352
    Location:212286
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:307360
    Homeobox; Homeobox domain