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Prat2 Phosphoribosylamidotransferase 2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38753, updated on 9-Dec-2024

Summary

Official Symbol
Prat2provided by FlyBase
Official Full Name
Phosphoribosylamidotransferase 2provided by FlyBase
Primary source
FLYBASE:FBgn0041194
Locus tag
Dmel_CG10078
See related
AllianceGenome:FB:FBgn0041194
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10078; Dmel\CG10078; DmPrat2
Summary
Predicted to enable amidophosphoribosyltransferase activity. Predicted to be involved in purine nucleotide biosynthetic process. Is expressed in adult head; adult heart; organism; and yolk nucleus. Orthologous to human PPAT (phosphoribosyl pyrophosphate amidotransferase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Prat2 in Genome Data Viewer
Location:
65D2-65D3; 3-18 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6911999..6914876, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6905099..6907976, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45115 Neighboring gene long non-coding RNA:CR45416 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
phosphoribosylamidotransferase 2
Names
CG10078-PA
CG10078-PB
Phosphoribosylamidotransferase-2
Prat2-PA
Prat2-PB
amidophosphoribosyltransferase
phosphoribosyl amidotransferase 2
NP_523949.2
NP_729191.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    6911999..6914876 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079225.3NP_523949.2  phosphoribosylamidotransferase 2, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523949.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q967S0
    Related
    FBpp0076654
    Conserved Domains (3) summary
    cd06223
    Location:351487
    PRTases_typeI; Phosphoribosyl transferase (PRT)-type I domain
    COG0034
    Location:57544
    PurF; Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]
    cd00715
    Location:58340
    GPATase_N; Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the ...
  2. NM_168181.2NP_729191.1  phosphoribosylamidotransferase 2, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729191.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VRZ1
    Related
    FBpp0076655
    Conserved Domains (3) summary
    cd06223
    Location:274410
    PRTases_typeI; Phosphoribosyl transferase (PRT)-type I domain
    COG0034
    Location:2467
    PurF; Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]
    cd00715
    Location:2263
    GPATase_N; Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the ...