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Cd300c CD300C molecule [ Mus musculus (house mouse) ]

Gene ID: 387565, updated on 9-Dec-2024

Summary

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Official Symbol
Cd300cprovided by MGI
Official Full Name
CD300C moleculeprovided by MGI
Primary source
MGI:MGI:3032626
See related
Ensembl:ENSMUSG00000058728 AllianceGenome:MGI:3032626
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Clm6
Summary
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in regulation of innate immune response and signal transduction. Predicted to be active in plasma membrane. Orthologous to human CD300C (CD300c molecule). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in spleen adult (RPKM 2.6), mammary gland adult (RPKM 1.2) and 5 other tissues See more
Orthologs
human all
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Genomic context

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See Cd300c in Genome Data Viewer
Location:
11 E2; 11 80.56 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (114846931..114851333, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (114956105..114960507, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene CD300A molecule Neighboring gene STARR-seq mESC enhancer starr_31138 Neighboring gene CD300 molecule like family member B Neighboring gene STARR-seq mESC enhancer starr_31139 Neighboring gene predicted gene 11699 Neighboring gene STARR-seq mESC enhancer starr_31140 Neighboring gene CD300 molecule like family member d Neighboring gene STARR-seq mESC enhancer starr_31141 Neighboring gene CD300C molecule 2 Neighboring gene CD300 molecule like family member D4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 is an FcRγ-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells. Kaitani A, et al. Sci Rep, 2018 May 29. PMID 29844322, Free PMC Article
  2. pDC-like cells are pre-DC2 and require KLF4 to control homeostatic CD4 T cells. Rodrigues PF, et al. Sci Immunol, 2023 Feb 24. PMID 36827419, Free PMC Article
  3. CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation. Chung DH, et al. J Immunol, 2003 Dec 15. PMID 14662855
  4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CLM-6 is an FcRgamma-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells
    Title: Leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 is an FcRγ-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables transmembrane signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in immune system process IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CMRF35-like molecule 6
Names
CD300 antigen-like family member C
CD300C antigen
CMRF-35-like molecule 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368239.1 → NP_001355168.1  CMRF35-like molecule 6 precursor

    Status: PROVISIONAL

    Source sequence(s)
    AL607025
    Consensus CDS
    CCDS88281.1
    UniProtKB/Swiss-Prot
    A2A7V7, Q6SJQ2
    UniProtKB/TrEMBL
    D3Z6G7
    Related
    ENSMUSP00000090123.7, ENSMUST00000092466.13

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    114846931..114851333 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_199225.1: Suppressed sequence

    Description
    NM_199225.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2A7V7.1 GenPept UniProtKB/Swiss-Prot:A2A7V7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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