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CG8641 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38771, updated on 4-Jan-2025

Summary

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Official Symbol
CG8641provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035733
Locus tag
Dmel_CG8641
See related
AllianceGenome:FB:FBgn0035733
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8641; Q9VS10
Summary
Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in signal transduction. Orthologous to several human genes including RASD2 (RASD family member 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG8641 in Genome Data Viewer
Location:
65E2-65E3; 3-19 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7058930..7077462, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7052030..7070562, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Multiplexin Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45832 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 65Ea Neighboring gene Cuticular protein 65Eb

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolutionary expansion of the Ras switch regulatory module in eukaryotes. Díez D, et al. Nucleic Acids Res, 2011 Jul. PMID 21447561, Free PMC Article
  2. Human RAS superfamily proteins and related GTPases. Colicelli J. Sci STKE, 2004 Sep 7. PMID 15367757, Free PMC Article
  3. Genome-wide view of cell fate specification: ladybird acts at multiple levels during diversification of muscle and heart precursors. Junion G, et al. Genes Dev, 2007 Dec 1. PMID 18056427, Free PMC Article
  4. Cellular diversity in the Drosophila midbrain revealed by single-cell transcriptomics. Croset V, et al. Elife, 2018 Apr 19. PMID 29671739, Free PMC Article
  5. The impact of genome variation and diet on the metabolic phenotype and microbiome composition of Drosophila melanogaster. Jehrke L, et al. Sci Rep, 2018 Apr 18. PMID 29670218, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables G-protein beta-subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8641-PA
CG8641-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    7058930..7077462 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274565.1 → NP_001261494.1  uncharacterized protein Dmel_CG8641, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261494.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VS10
    Conserved Domains (2) summary
    cd04143
    Location:167 → 434
    Rhes_like; Ras homolog enriched in striatum (Rhes) and activator of G-protein signaling 1 (Dexras1/AGS1)
    smart00173
    Location:167 → 338
    RAS; Ras subfamily of RAS small GTPases

  2. NM_139816.2 → NP_648073.1  uncharacterized protein Dmel_CG8641, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648073.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VS10
    Related
    FBpp0076640
    Conserved Domains (2) summary
    cd04143
    Location:167 → 434
    Rhes_like; Ras homolog enriched in striatum (Rhes) and activator of G-protein signaling 1 (Dexras1/AGS1)
    smart00173
    Location:167 → 338
    RAS; Ras subfamily of RAS small GTPases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VS10 Q9VS10

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