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Sec63 - Secretory 63

Predicted to enable protein transmembrane transporter activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane and post-translational protein targeting to endoplasmic reticulum membrane. Located in fusome. Is expressed in several structures, including adult head; embryonic dorsal epidermis; embryonic hypopharynx; embryonic/larval salivary gland; and gut section. Human ortholog(s) of this gene implicated in polycystic liver disease 2. Orthologous to human SEC63 (SEC63 homolog, protein translocation regulator). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa