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Srp9 Signal recognition particle 9 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38883, updated on 4-Jan-2025

Summary

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Official Symbol
Srp9provided by FlyBase
Official Full Name
Signal recognition particle 9provided by FlyBase
Primary source
FLYBASE:FBgn0035827
Locus tag
Dmel_CG8268
See related
AllianceGenome:FB:FBgn0035827
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8268; Dmel\CG8268; SRP9
Summary
Predicted to enable 7S RNA binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Is expressed in adult head; embryonic/larval salivary gland; embryonic/larval salivary gland body; organism; and salivary gland body primordium. Orthologous to human SRP9 (signal recognition particle 9). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Srp9 in Genome Data Viewer
Location:
66A20-66A20; 3-21 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7936373..7937258)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7929473..7930358)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR32368 Neighboring gene sunday driver Neighboring gene uncharacterized protein Neighboring gene extra-extra

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nascent polypeptide-Associated Complex and Signal Recognition Particle have cardiac-specific roles in heart development and remodeling. Schroeder AM, et al. PLoS Genet, 2022 Oct. PMID 36240221, Free PMC Article
  2. The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. Fox RM, et al. J Cell Biol, 2010 Nov 1. PMID 21041443, Free PMC Article
  3. CrebA regulates secretory activity in the Drosophila salivary gland and epidermis. Abrams EW, et al. Development, 2005 Jun. PMID 15901661
  4. Genome-wide P-element screen for Drosophila synaptogenesis mutants. Liebl FL, et al. J Neurobiol, 2006 Mar. PMID 16408305, Free PMC Article
  5. C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Lee KH, et al. Cell, 2016 Oct 20. PMID 27768896, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables 7S RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in SRP-dependent cotranslational protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in SRP-dependent cotranslational protein targeting to membrane IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of translational elongation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of signal recognition particle IEA
Inferred from Electronic Annotation
more info
  
part_of signal recognition particle, endoplasmic reticulum targeting IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
signal recognition particle 9
Names
CG8268-PA
Srp9-PA
signal recognition particle protein 9

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    7936373..7937258
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139906.3 → NP_648163.1  signal recognition particle 9 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648163.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VSC1
    Related
    FBpp0076467
    Conserved Domains (1) summary
    pfam05486
    Location:4 → 73
    SRP9-21; Signal recognition particle 9 kDa protein (SRP9)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VSC1.1 Q9VSC1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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