Hsp67Bc - Heat shock gene 67Bc
Predicted to enable unfolded protein binding activity. Involved in regulation of autophagy; regulation of protein metabolic process; and response to heat. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including embryonic head sensory system; ganglia; sensory nervous system primordium; and yolk nucleus. Used to study Charcot-Marie-Tooth disease axonal type 2L and autosomal dominant distal hereditary motor neuronopathy 2. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Orthologous to human CRYAA (crystallin alpha A). [provided by Alliance of Genome Resources, Nov 2024]
NCBI Orthologs
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Protein alignment
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