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Prps - Phosphoribosyl pyrophosphate synthetase

Predicted to enable ribose phosphate diphosphokinase activity. Involved in olfactory behavior. Predicted to be part of ribose phosphate diphosphokinase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including adult head; adult heart; embryonic anal pad; larval muscle cell; and visceral mesoderm derivative. Human ortholog(s) of this gene implicated in Arts syndrome; X-linked deafness 1; X-linked recessive disease (multiple); gout; and retinitis pigmentosa. Orthologous to human PRPS1 (phosphoribosyl pyrophosphate synthetase 1); PRPS1L1 (phosphoribosyl pyrophosphate synthetase 1 like 1); and PRPS2 (phosphoribosyl pyrophosphate synthetase 2). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa