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Ae2 - Anion exchanger 2

Predicted to enable transmembrane transporter activity. Involved in intracellular pH reduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adult brain; adult head; embryonic/larval midgut; ganglia; and larval midgut enterocyte. Human ortholog(s) of this gene implicated in congenital hemolytic anemia; hereditary spherocytosis; osteopetrosis; and renal tubular acidosis. Orthologous to human SLC4A1 (solute carrier family 4 member 1 (Diego blood group)); SLC4A2 (solute carrier family 4 member 2); and SLC4A3 (solute carrier family 4 member 3). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to Ae2

NCBI Orthologs

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Species Gene Architecture aa