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iPLA2-VIA - calcium-independent phospholipase A2 VIA

Enables retromer complex binding activity. Involved in positive regulation of response to oxidative stress; regulation of ceramide biosynthetic process; and triglyceride homeostasis. Located in mitochondrion. Is expressed in several structures, including adult head; central brain primordium; embryonic/larval garland cell; ganglia; and primordial germ cell. Used to study Parkinson's disease 14; neurodegeneration with brain iron accumulation 2a; and neurodegenerative disease. Human ortholog(s) of this gene implicated in dystonia 12; neuroaxonal dystrophy; and neurodegenerative disease (multiple). Orthologous to human PLA2G6 (phospholipase A2 group VI). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to iPLA2-VIA

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Species Gene Architecture aa