Rbfox1 - RNA-binding Fox protein 1
Enables DNA-binding transcription factor binding activity; mRNA 3'-UTR binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including germarium-derived oocyte differentiation; imaginal disc-derived wing vein specification; and regulation of gene expression. Located in nuclear lumen and ribonucleoprotein granule. Is expressed in several structures, including developmental compartment; epithelium; imaginal disc; muscle cell; and somatic precursor cell. Used to study intellectual disability. Human ortholog(s) of this gene implicated in congenital heart disease. Orthologous to human RBFOX1 (RNA binding fox-1 homolog 1); RBFOX2 (RNA binding fox-1 homolog 2); and RBFOX3 (RNA binding fox-1 homolog 3). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
How was this calculated?genes for:
Protein alignment
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