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CG6321 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39233, updated on 4-Jan-2025

Summary

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Official Symbol
CG6321provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036117
Locus tag
Dmel_CG6321
See related
AllianceGenome:FB:FBgn0036117
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG6321
Summary
Predicted to enable 2-aminoadipate transaminase activity and kynurenine-oxoglutarate transaminase activity. Predicted to be involved in biosynthetic process. Predicted to be active in cytosol and mitochondrial matrix. Is expressed in several structures, including adult fat body; gland; and gut section. Orthologous to human AADAT (aminoadipate aminotransferase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG6321 in Genome Data Viewer
Location:
68A3-68A3; 3-34 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11059437..11061224, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11052537..11054324, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44547 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45119 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Biogenesis of lysosome-related organelles complex 1, subunit 2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Drosophila suppressor of underreplication protein binds to late-replicating regions of polytene chromosomes. Makunin IV, et al. Genetics, 2002 Mar. PMID 11901119, Free PMC Article
  2. The Recent De Novo Origin of Protein C-Termini. Andreatta ME, et al. Genome Biol Evol, 2015 May 21. PMID 26002864, Free PMC Article
  3. The circadian clock interacts with metabolic physiology to influence reproductive fitness. Xu K, et al. Cell Metab, 2011 Jun 8. PMID 21641546, Free PMC Article
  4. Analysis of Ras-induced overproliferation in Drosophila hemocytes. Asha H, et al. Genetics, 2003 Jan. PMID 12586708, Free PMC Article
  5. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables 2-aminoadipate transaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 2-aminoadipate transaminase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables kynurenine-oxoglutarate transaminase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in mitochondrial matrix ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6321-PA
NP_648426.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    11059437..11061224 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140169.4 → NP_648426.1  uncharacterized protein Dmel_CG6321 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648426.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VTD9
    Related
    FBpp0075971
    Conserved Domains (2) summary
    cd00609
    Location:27 → 407
    AAT_like; Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine ...
    COG0436
    Location:25 → 414
    AspB; Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VTD9 Q9VTD9

Gene LinkOut

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