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emei emei [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39250, updated on 9-Dec-2024

Summary

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Official Symbol
emeiprovided by FlyBase
Official Full Name
emeiprovided by FlyBase
Primary source
FLYBASE:FBgn0036133
Locus tag
Dmel_CG7638
See related
AllianceGenome:FB:FBgn0036133
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7638; Dmel\CG7638
Summary
Involved in positive regulation of endoplasmic reticulum calcium ion concentration. Located in endoplasmic reticulum. Is expressed in several structures, including gut section; head epidermis primordium; larval muscle cell; mesoderm; and visceral mesoderm derivative. Orthologous to human TMEM161A (transmembrane protein 161A) and TMEM161B (transmembrane protein 161B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See emei in Genome Data Viewer
Location:
68A7-68A7; 3-34 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11109690..11112117)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11102790..11105217)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Superoxide dismutase 1 Neighboring gene Forkhead box K

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel regulator of ER Ca(2+) drives Hippo-mediated tumorigenesis. Ma X, et al. Oncogene, 2020 Feb. PMID 31649333
  2. The MOF chromobarrel domain controls genome-wide H4K16 acetylation and spreading of the MSL complex. Conrad T, et al. Dev Cell, 2012 Mar 13. PMID 22421046
  3. Laser microdissection of sensory organ precursor cells of Drosophila microchaetes. Buffin E, et al. PLoS One, 2010 Feb 19. PMID 20174573, Free PMC Article
  4. A genetic interaction map of cell cycle regulators. Billmann M, et al. Mol Biol Cell, 2016 Apr 15. PMID 26912791, Free PMC Article
  5. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in positive regulation of endoplasmic reticulum calcium ion concentration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
emei
Names
CG7638-PA
emei-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    11109690..11112117
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140182.3 → NP_648439.1  emei [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648439.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VTF5
    Related
    FBpp0075940
    Conserved Domains (1) summary
    pfam10268
    Location:2 → 493
    Tmemb_161AB; Predicted transmembrane protein 161AB
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VTF5 Q9VTF5

Gene LinkOut

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