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CG14142 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39261, updated on 9-Dec-2024

Summary

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Official Symbol
CG14142provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036143
Locus tag
Dmel_CG14142
See related
AllianceGenome:FB:FBgn0036143
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG14142
Summary
Predicted to enable K48-linked deubiquitinase activity. Predicted to be involved in protein K48-linked deubiquitination. Orthologous to several human genes including MINDY4B (MINDY family member 4B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG14142 in Genome Data Viewer
Location:
68A9-68B1; 3-35 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11173514..11176892)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11166614..11169992)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene ALG10 alpha-1,2-glucosyltransferase Neighboring gene wntless Neighboring gene aarF domain containing kinase 5 Neighboring gene Glucuronyltransferase P Neighboring gene procollagen lysyl hydroxylase Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The glucuronyltransferase GlcAT-P is required for stretch growth of peripheral nerves in Drosophila. Pandey R, et al. PLoS One, 2011. PMID 22132223, Free PMC Article
  2. Molecular Profiling of the Drosophila Antenna Reveals Conserved Genes Underlying Olfaction in Insects. Mohapatra P, et al. G3 (Bethesda), 2019 Nov 5. PMID 31527046, Free PMC Article
  3. The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster. Zhou S, et al. Environ Health Perspect, 2016 Jul. PMID 26859824, Free PMC Article
  4. Comparative exploration of mammalian deafness gene homologues in the Drosophila auditory organ shows genetic correlation between insect and vertebrate hearing. Sutton DC, et al. PLoS One, 2024. PMID 38412189, Free PMC Article
  5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables K48-linked deubiquitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables K48-linked deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
  
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein K48-linked deubiquitination IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG14142-PB
CG14142-PC
CG14142-PD
NP_001163415.1
NP_001163416.1
NP_648447.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    11173514..11176892
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001169944.1 → NP_001163415.1  uncharacterized protein Dmel_CG14142, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163415.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JID2
    Conserved Domains (1) summary
    pfam13898
    Location:22 → 181
    DUF4205; Domain of unknown function (DUF4205)

  2. NM_001169945.1 → NP_001163416.1  uncharacterized protein Dmel_CG14142, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163416.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JID3
    Conserved Domains (1) summary
    pfam13898
    Location:22 → 191
    DUF4205; Domain of unknown function (DUF4205)

  3. NM_140190.2 → NP_648447.2  uncharacterized protein Dmel_CG14142, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648447.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VTG6
    Conserved Domains (1) summary
    pfam13898
    Location:22 → 433
    DUF4205; Domain of unknown function (DUF4205)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E1JID2 E1JID2
E1JID3 E1JID3
Q9VTG6 Q9VTG6

Gene LinkOut

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