Plod - procollagen lysyl hydroxylase

Enables procollagen galactosyltransferase activity and procollagen glucosyltransferase activity. Involved in growth of a germarium-derived egg chamber. Located in endoplasmic reticulum; extracellular space; and perinuclear region of cytoplasm. Is expressed in several structures, including adult head; embryonic/larval anal pad; embryonic/larval hemocyte; nurse cell; and visceral mesoderm derivative. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome kyphoscoliotic type 1. Orthologous to several human genes including PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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