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Sgs3 Salivary gland secretion 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39288, updated on 9-Dec-2024

Summary

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Official Symbol
Sgs3provided by FlyBase
Official Full Name
Salivary gland secretion 3provided by FlyBase
Primary source
FLYBASE:FBgn0003373
Locus tag
Dmel_CG11720
See related
AllianceGenome:FB:FBgn0003373
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
68C GII; CG11720; Dmel\CG11720; DMSGS378; Glue; Muc68Cb; Sgs; sgs-3; Sgs-3; SGS-3; sgs3; SGS378
Summary
Predicted to be an extracellular matrix structural constituent. Involved in puparial adhesion. Located in adhesive extracellular matrix. Is expressed in several structures, including adult heart; embryonic/larval Malpighian tubule; embryonic/larval fat body; embryonic/larval proventriculus; and salivary gland. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Sgs3 in Genome Data Viewer
Location:
68C11-68C11; 3-36 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11512221..11513402)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11505321..11506502)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Salivary gland secretion 7 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene alpha-L-fucosidase Neighboring gene Mob2 Neighboring gene mir-4968 stem loop

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gross morphology and adhesion-associated physical properties of Drosophila larval salivary gland glue secretion. Beňo M, et al. Sci Rep, 2024 Apr 29. PMID 38684688, Free PMC Article
  2. Starvation selection reduces and delays larval ecdysone production and signaling. Clark JM, et al. J Exp Biol, 2023 Sep 15. PMID 37671530, Free PMC Article
  3. Drosophila glue gene Sgs-3: sequences required for puffing and transcriptional regulation. Crosby MA, et al. Dev Biol, 1986 Dec. PMID 2431935
  4. Evolution and expression of the Sgs-3 glue gene of Drosophila. Martin CH, et al. J Mol Biol, 1988 May 20. PMID 3138416
  5. Drosophila Sgs3 TATA: effects of point mutations on expression in vivo and protein binding in vitro with staged nuclear extracts. Giangrande A, et al. EMBO J, 1989 Nov. PMID 2583107, Free PMC Article

See all (165) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. stage-precocious activation of Sgs3 required expression of the Broad-complex, similar to normal Sgs3 developmental regulation, and a small level of nutritional input.
    Title: Glue protein production can be triggered by steroid hormone signaling independent of the developmental program in Drosophila melanogaster.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables extracellular matrix structural constituent ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in puparial adhesion IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in adhesive extracellular matrix IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
salivary gland secretion 3
Names
CG11720-PA
Sgs3-PA
gene IV
group IV
mucin 68Cb
salivary gland glue protein 3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    11512221..11513402
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079300.3 → NP_524024.1  salivary gland secretion 3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524024.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02840, Q9VTJ2
    Related
    FBpp0075827
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P02840.1 P02840

Gene LinkOut

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