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Polr3H RNA polymerase III subunit H [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39310, updated on 9-Dec-2024

Summary

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Official Symbol
Polr3Hprovided by FlyBase
Official Full Name
RNA polymerase III subunit Hprovided by FlyBase
Primary source
FLYBASE:FBgn0036188
Locus tag
Dmel_CG7339
See related
AllianceGenome:FB:FBgn0036188
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7339; Dmel\CG7339; lincRNA.S4825; RPC25
Summary
Predicted to be involved in transcription initiation at RNA polymerase III promoter. Predicted to be part of RNA polymerase III complex. Orthologous to human POLR3H (RNA polymerase III subunit H). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Polr3H in Genome Data Viewer
Location:
68D1-68D1; 3-36 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11648756..11650499)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11641856..11643599)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene RIO kinase 1 Neighboring gene uncharacterized protein Neighboring gene mir-274 stem loop Neighboring gene long non-coding RNA:CR45881

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Tendon Cell Specific RNAi Screen Reveals Novel Candidates Essential for Muscle Tendon Interaction. Tiwari P, et al. PLoS One, 2015. PMID 26488612, Free PMC Article
  2. In silico identification of Drosophila melanogaster genes encoding RNA polymerase subunits. Marygold SJ, et al. MicroPubl Biol, 2020 Oct 20. PMID 33274328, Free PMC Article
  3. A transcriptome-wide RNAi screen in the Drosophila ovary reveals factors of the germline piRNA pathway. Czech B, et al. Mol Cell, 2013 Jun 6. PMID 23665227, Free PMC Article
  4. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article
  5. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA-templated transcription initiation IEA
Inferred from Electronic Annotation
more info
  
involved_in transcription initiation at RNA polymerase III promoter IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RNA polymerase III subunit H
Names
CG7339-PA
CG7339-PB
Polr3H-PA
Polr3H-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    11648756..11650499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274791.1 → NP_001261720.1  RNA polymerase III subunit H, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261720.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VTL6
    Conserved Domains (3) summary
    COG1095
    Location:1 → 212
    RPB7; DNA-directed RNA polymerase, subunit E'/Rpb7 [Transcription]
    cd04330
    Location:2 → 81
    RNAP_III_Rpc25_N; RNAP_III_Rpc25_N: Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains, ...
    pfam08292
    Location:79 → 212
    RNA_pol_Rbc25; RNA polymerase III subunit Rpc25

  2. NM_140233.2 → NP_648490.1  RNA polymerase III subunit H, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648490.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VTL6
    Related
    FBpp0075838
    Conserved Domains (3) summary
    COG1095
    Location:1 → 212
    RPB7; DNA-directed RNA polymerase, subunit E'/Rpb7 [Transcription]
    cd04330
    Location:2 → 81
    RNAP_III_Rpc25_N; RNAP_III_Rpc25_N: Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains, ...
    pfam08292
    Location:79 → 212
    RNA_pol_Rbc25; RNA polymerase III subunit Rpc25
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VTL6 Q9VTL6

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