CCDC151 Coiled-coil domain containing protein 151 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CCDC151provided by FlyBase
Official Full Name: Coiled-coil domain containing protein 151provided by FlyBase
Primary source: FLYBASE:FBgn0036219
Locus tag: Dmel_CG14127
See related: AllianceGenome:FB:FBgn0036219
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Ccdc151; CG14127; Dmel\CG14127
Summary: Involved in negative gravitaxis. Located in several cellular components, including cell body; ciliary rootlet; and ciliary tip. Is expressed in chordotonal neurons and chordotonal organ. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 30. Orthologous to human ODAD3 (outer dynein arm docking complex subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (11881384..11883546)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (11874484..11876646)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in axonemal dynein complex assembly	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in cilium movement	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium movement	IEA Inferred from Electronic Annotation more info
involved_in cilium movement	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in negative gravitaxis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in outer dynein arm assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in outer dynein arm assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cell body	IDA Inferred from Direct Assay more info	PubMed
is_active_in ciliary basal body	IBA Inferred from Biological aspect of Ancestor more info
is_active_in ciliary rootlet	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary rootlet	IDA Inferred from Direct Assay more info	PubMed
is_active_in ciliary tip	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary tip	IDA Inferred from Direct Assay more info	PubMed
located_in cilium	IEA Inferred from Electronic Annotation more info
located_in motile cilium	IDA Inferred from Direct Assay more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain