lbh LBH regulator of WNT signaling pathway [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: lbhprovided by ZNC
Official Full Name: LBH regulator of WNT signaling pathwayprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1613
See related: Ensembl:ENSDARG00000111701 AllianceGenome:ZFIN:ZDB-GENE-040426-1613
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:66337
Summary: Acts upstream of or within embryonic viscerocranium morphogenesis and neural crest cell migration. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; digestive system; head; neural crest cell; and pleuroperitoneal region. Orthologous to human LBH (LBH regulator of WNT signaling pathway). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (51843154..51851143, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (51610559..51617621, complement)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

G46502 (e-PCR)
- UniSTS:107304

G47834 (e-PCR)
- UniSTS:108603

z1496 (e-PCR), detects polymorphism
- UniSTS:205130

G40118 (e-PCR)
- UniSTS:9615

fb81g02.x1 (e-PCR)
- UniSTS:191647

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within embryonic viscerocranium morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within neural crest cell migration	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein LBH

Names: limb bud and heart development homolog-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.