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cct8 chaperonin containing TCP1, subunit 8 (theta) [ Danio rerio (zebrafish) ]

Gene ID: 394037, updated on 4-Jan-2025

Summary

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Official Symbol
cct8provided by ZNC
Official Full Name
chaperonin containing TCP1, subunit 8 (theta)provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-876
See related
Ensembl:ENSDARG00000008243 AllianceGenome:ZFIN:ZDB-GENE-040426-876
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa22h09; zgc:56059; wu:fa22h09
Summary
Predicted to enable unfolded protein binding activity. Acts upstream of or within behavioral response to nicotine. Predicted to be part of chaperonin-containing T-complex. Is expressed in brain. Orthologous to human CCT8 (chaperonin containing TCP1 subunit 8). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See cct8 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (25329582..25342960, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (25367309..25383225, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene RAB38b, member of RAS oncogene family Neighboring gene transmembrane protein 135 Neighboring gene map3k7 C-terminal like Neighboring gene BTB and CNC homology 1, basic leucine zipper transcription factor 1 b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Nicotine response genetics in the zebrafish. Petzold AM, et al. Proc Natl Acad Sci U S A, 2009 Nov 3. PMID 19858493, Free PMC Article
  2. The spatial-temporal expression and functional divergence of bach homologs in zebrafish Danio rerio. Luo Q, et al. J Fish Biol, 2016 Apr. PMID 26992035
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC56059

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent protein folding chaperone IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within behavioral response to nicotine IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein folding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of chaperonin-containing T-complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
T-complex protein 1 subunit theta
Names
bdav
bette davis

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201062.1 → NP_957356.1  T-complex protein 1 subunit theta

    See identical proteins and their annotated locations for NP_957356.1

    Status: PROVISIONAL

    Source sequence(s)
    BC050492
    UniProtKB/TrEMBL
    B2GQA3, F6NVA7, Q7ZU96
    Related
    ENSDARP00000003468.5, ENSDART00000009477.6
    Conserved Domains (2) summary
    TIGR02346
    Location:10 → 539
    chap_CCT_theta; T-complex protein 1, theta subunit
    pfam00118
    Location:39 → 528
    Cpn60_TCP1; TCP-1/cpn60 chaperonin family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    25329582..25342960 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005155366.4 → XP_005155423.1  T-complex protein 1 subunit theta isoform X1

    UniProtKB/TrEMBL
    A0A0R4IJT8, A0A8M2B296
    Related
    ENSDARP00000135440.1, ENSDART00000166348.2
    Conserved Domains (2) summary
    TIGR02346
    Location:10 → 539
    chap_CCT_theta; T-complex protein 1, theta subunit
    pfam00118
    Location:39 → 528
    Cpn60_TCP1; TCP-1/cpn60 chaperonin family
Nucleotide Protein Strain
Heading Accession and Version

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