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ventx2.2.L VENT homeobox 2, gene 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 394272, updated on 4-Jan-2025

Summary

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Official Symbol
ventx2.2.L
Official Full Name
VENT homeobox 2, gene 2 L homeolog
Primary source
Xenbase:XB-GENE-920534
Locus tag
XELAEV_18034615mg
See related
EnsemblRapid:ENSXLAG00005014418 AllianceGenome:Xenbase:XB-GENE-920534
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
Xom; vox; vent2; xom-A; vent-2; xvent2; xvent-2; ventx2.2
Summary
Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to act upstream of or within regulation of DNA-templated transcription and spinal cord motor neuron cell fate specification. Predicted to be located in nucleus. Is expressed in anatomical system and primary germ layer. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ventx2.2.L in Genome Data Viewer
Location:
chromosome: 7L
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7L NC_054383.1 (21777297..21779193)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7L NC_030736.1 (21829663..21831559)

Chromosome 7L - NC_054383.1Genomic Context describing neighboring genes Neighboring gene VENT homeobox 3, gene 2 L homeolog Neighboring gene VENT homeobox 1, gene 2 L homeolog Neighboring gene VENT homeobox 1 gene 1 L homeolog Neighboring gene VENT homeobox 2 gene 1 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Xom: a Xenopus homeobox gene that mediates the early effects of BMP-4. Ladher R, et al. Development, 1996 Aug. PMID 8756284
  2. Xom interacts with and stimulates transcriptional activity of LEF1/TCFs: implications for ventral cell fate determination during vertebrate embryogenesis. Gao H, et al. Cell Res, 2007 Apr. PMID 17404593
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within spinal cord motor neuron cell fate specification IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
VENT homeobox 2, gene 2 L homeolog
Names
homeobox protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087462.1 → NP_001080931.1  VENT homeobox 2, gene 2 L homeolog

    See identical proteins and their annotated locations for NP_001080931.1

    Status: PROVISIONAL

    Source sequence(s)
    X98454
    UniProtKB/TrEMBL
    Q91914, Q9DG85
    Related
    ENSXLAP00005042211.1, ENSXLAT00005043277.1
    Conserved Domains (1) summary
    pfam00046
    Location:178 → 230
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    21777297..21779193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials