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MICAL-like MICAL-like [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39475, updated on 9-Dec-2024

Summary

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Official Symbol
MICAL-likeprovided by FlyBase
Official Full Name
MICAL-likeprovided by FlyBase
Primary source
FLYBASE:FBgn0036333
Locus tag
Dmel_CG11259
See related
AllianceGenome:FB:FBgn0036333
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AAK93415; CG11259; Dmel\CG11259
Summary
Involved in endocytic recycling. Is active in terminal bouton. Is expressed in several structures, including Malpighian tubule primordium; embryonic epipharynx; embryonic/larval midgut primordium; epithelium; and gut section. Orthologous to several human genes including MICALL1 (MICAL like 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See MICAL-like in Genome Data Viewer
Location:
69F5-69F5; 3-39 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (13011976..13015332, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (13005076..13008432, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene Cullin 6 Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein L20

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. MICAL-like Regulates Fasciclin II Membrane Cycling and Synaptic Development. Nahm M, et al. Mol Cells, 2016 Oct. PMID 27770767, Free PMC Article
  2. Calponin homology domains at a glance. Korenbaum E, et al. J Cell Sci, 2002 Sep 15. PMID 12186940
  3. Flying through the drosophila cytoskeletal genome. Goldstein LS, et al. J Cell Biol, 2000 Jul 24. PMID 10908588, Free PMC Article
  4. The Roles of the LIM Domain Proteins in Drosophila Cardiac and Hematopoietic Morphogenesis. She M, et al. Front Cardiovasc Med, 2021. PMID 33681304, Free PMC Article
  5. Burst of young retrogenes and independent retrogene formation in mammals. Pan D, et al. PLoS One, 2009. PMID 19325906, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endocytic recycling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in terminal bouton IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
MICAL-like
Names
CG11259-PA
MICAL-like-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    13011976..13015332 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140364.3 → NP_648621.1  MICAL-like [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648621.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q960L8, Q9VU34
    Related
    FBpp0075632
    Conserved Domains (3) summary
    cd09400
    Location:146 → 207
    LIM_like_1; LIM domain in proteins of unknown function
    pfam00307
    Location:14 → 111
    CH; Calponin homology (CH) domain
    pfam12130
    Location:778 → 933
    DUF3585; Protein of unknown function (DUF3585)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VU34 Q9VU34

Gene LinkOut

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