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SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 [ Gallus gallus (chicken) ]

Gene ID: 395202, updated on 3-Dec-2024

Summary

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Symbol
SH3GL1provided by CGNC
Full Name
SH3 domain containing GRB2 like 1, endophilin A2provided by CGNC
Primary source
CGNC:49210
See related
Ensembl:ENSGALG00010027192
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
SH3P8
Orthologs
human mouse all
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Genomic context

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See SH3GL1 in Genome Data Viewer
Location:
chromosome: 28
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 28 NC_052559.1 (2914322..2940969, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 28 NC_052600.1 (2480362..2507017, complement)

Chromosome 28 - NC_052559.1Genomic Context describing neighboring genes Neighboring gene mex-3 RNA binding family member D Neighboring gene MIER family member 2 Neighboring gene chromatin assembly factor 1 subunit A Neighboring gene UBX domain protein 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Receptor-mediated chicken oocyte growth: differential expression of endophilin isoforms in developing follicles. Hirayama S, et al. Biol Reprod, 2003 May. PMID 12606338
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in synaptic vesicle uncoating IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
endophilin-A2
Names
SH3 domain-containing GRB2-like protein 2
SH3-domain GRB2-like 1
endophilin II
endophilin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204529.2 → NP_989860.1  endophilin-A2

    See identical proteins and their annotated locations for NP_989860.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000375
    UniProtKB/Swiss-Prot
    Q8AXV0
    UniProtKB/TrEMBL
    A0A8V1AAE6
    Related
    ENSGALP00010040194.1, ENSGALT00010065928.1
    Conserved Domains (2) summary
    cd07614
    Location:25 → 247
    BAR_Endophilin_A2; The Bin/Amphiphysin/Rvs (BAR) domain of Endophilin-A2
    cd11803
    Location:308 → 362
    SH3_Endophilin_A; Src homology 3 domain of Endophilin-A

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052559.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2914322..2940969 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015299915.4 → XP_015155401.2  endophilin-A2 isoform X2

    UniProtKB/TrEMBL
    A0A8V1A7T9
    Related
    ENSGALP00010040197.1, ENSGALT00010065931.1
    Conserved Domains (2) summary
    cd07614
    Location:25 → 247
    BAR_Endophilin_A2; The Bin/Amphiphysin/Rvs (BAR) domain of Endophilin-A2
    cd11803
    Location:290 → 344
    SH3_Endophilin_A; Src homology 3 domain of Endophilin-A

  2. XM_046904526.1 → XP_046760482.1  endophilin-A2 isoform X4

    UniProtKB/TrEMBL
    A0A8V1AAE6

  3. XM_015299917.3 → XP_015155403.2  endophilin-A2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1A7T9
    Conserved Domains (2) summary
    cd11803
    Location:279 → 333
    SH3_Endophilin_A; Src homology 3 domain of Endophilin-A
    cl12013
    Location:14 → 236
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  4. XM_015299916.4 → XP_015155402.2  endophilin-A2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AAE6
    Conserved Domains (2) summary
    cd07614
    Location:14 → 236
    BAR_Endophilin_A2; The Bin/Amphiphysin/Rvs (BAR) domain of Endophilin-A2
    cd11803
    Location:297 → 351
    SH3_Endophilin_A; Src homology 3 domain of Endophilin-A

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052600.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2480362..2507017 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046933670.1 → XP_046789626.1  endophilin-A2 isoform X2

    UniProtKB/TrEMBL
    A0A8V1A7T9

  2. XM_046933669.1 → XP_046789625.1  endophilin-A2 isoform X6

    UniProtKB/TrEMBL
    A0A8V1A7T9

  3. XM_046933668.1 → XP_046789624.1  endophilin-A2 isoform X5

    UniProtKB/TrEMBL
    A0A8V1AAE6
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8AXV0.1 GenPept UniProtKB/Swiss-Prot:Q8AXV0

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