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Nprl3 - Nitrogen permease regulator-like 3

Involved in several processes, including cellular response to amino acid starvation; negative regulation of TORC1 signaling; and negative regulation of cell size. Located in autolysosome and nucleus. Part of GATOR2 complex. Is expressed in organism. Used to study familial focal epilepsy with variable foci 3. Human ortholog(s) of this gene implicated in familial focal epilepsy with variable foci 3. Orthologous to human NPRL3 (NPR3 like, GATOR1 complex subunit). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa