RDX radixin [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: RDXprovided by CGNC
Official Full Name: radixinprovided by CGNC
Primary source: CGNC:49356
See related: Ensembl:ENSGALG00010005363
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (179478699..179514342)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (179511202..179546849)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Ezrin/radixin/moesin proteins organize actin filaments in sensory neuron growth cones and are crucial for neurotrophin-induced remodeling of F-actin and redistribution of adhesion receptors.
Title: Activation of ezrin/radixin/moesin mediates attractive growth cone guidance through regulation of growth cone actin and adhesion receptors.
Radixin is a prominent constituent of stereocilia, where it may participate in anchoring the "pointed" ends of actin filaments to the membrane
Title: Radixin is a constituent of stereocilia in hair cells.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cell adhesion molecule binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of early endosome to late endosome transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of protein localization to early endosome	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell shape	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of organelle assembly	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in adherens junction	IEA Inferred from Electronic Annotation more info	PubMed
located_in apical part of cell	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info	PubMed
located_in filopodium	IEA Inferred from Electronic Annotation more info	PubMed
located_in microvillus	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: radixin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204751.2 → NP_990082.2 radixin

Status: PROVISIONAL

Source sequence(s)

JAENSK010000027

UniProtKB/Swiss-Prot

Q9PU45

Related

ENSGALP00010007297.1, ENSGALT00010012733.1

Conserved Domains (3) summary

smart00295
Location:7 → 206

B41; Band 4.1 homologues

cd13194
Location:200 → 296

FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family

TIGR02168
Location:307 → 583

SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

179478699..179514342

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040649097.2 → XP_040505031.1 radixin isoform X1

UniProtKB/Swiss-Prot

Q9PU45

Conserved Domains (3) summary

smart00295
Location:7 → 206

B41; Band 4.1 homologues

cd13194
Location:200 → 296

FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family

TIGR02168
Location:307 → 583

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_040649071.2 → XP_040505005.1 radixin isoform X1

UniProtKB/Swiss-Prot

Q9PU45

Conserved Domains (3) summary

smart00295
Location:7 → 206

B41; Band 4.1 homologues

cd13194
Location:200 → 296

FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family

TIGR02168
Location:307 → 583

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_015277633.3 → XP_015133119.2 radixin isoform X2

Conserved Domains (3) summary

smart00295
Location:27 → 70

B41; Band 4.1 homologues

cd13194
Location:64 → 160

FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family

TIGR02168
Location:171 → 447

SMC_prok_B; chromosome segregation protein SMC, common bacterial type