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btl - breathless

Enables fibroblast growth factor receptor activity. Involved in several processes, including border follicle cell migration; negative regulation of cell differentiation; and open tracheal system development. Located in plasma membrane. Colocalizes with cytoneme. Is expressed in several structures, including abdominal tracheal metamere; epithelium; imaginal disc; primary segmental tracheal branch primordium; and tracheal system. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); carcinoma (multiple); gastrointestinal system cancer (multiple); osteochondrodysplasia (multiple); and synostosis (multiple). Orthologous to human FGFR2 (fibroblast growth factor receptor 2); FGFR3 (fibroblast growth factor receptor 3); and FGFR4 (fibroblast growth factor receptor 4). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to btl

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Species Gene Architecture aa